Low Dose Naltrexone – LDN

Naltrexone is in a class of drug known as an opiate antagonists. Its normal use is in treating addiction to opiate drugs such as heroin or morphine. The dose used for this purpose is usually between 50 and 300mg daily.  Low Dose Naltrexone (1.5mg – 4.5mg daily), on the other hand, has been prescribes for patients with the following conditions: Cardiac (Heart) Diseases, Chronic Pain, Dermatologic (Skin) diseases, Ear/Nose/Sinus/Throat disorders, Endocrine Diseases, Gastrointestinal Diseases, Hematologic (Blood) Disorders, Hepatology (Liver) Diseases, Immunologic (Immune System) Disorders, Infectious Diseases, Malignancies/Cancers, Neurologic Diseases, Ocular (Eye) Diseases, Pulmonary (Lung) Diseases, Renal (Kidney) Diseases, Rheumatologic (Arthritis) Disorders, Sleep Disorders, Vasculits and Women’s Health Disorders.

How does LDN work?

Naltrexone is a 50:50 mixture of 2 medications (called isomers) in one.  One isomer binds to immune cells, while the other isomer binds to opioid receptors.  Taking Naltrexone in the larger dose range of 50gm – 300mg daily negates the immunomodulatory effect by oversaturating the receptors, therefore, the dose must be in the range of 1.5mg – 4.5mg in order to take advantage of both its Immunologic and Opioid binding effects.  Clinically, patients report that the benefits of LDN start at about 2-3 weeks into therapy with a maximal effect observed at about 2 months.  LDN is well tolerated but some side effects may occur, especially at the beginning of therapy.  The side effects may include Insomnia, Vivid Dream and even Headaches.  These side effects usually improve within a few days after continued use.

 How to determine if LDN is right for me?

The physicians of the Longevity & Stem Cell Centre of Houston prefer the following titration schedule for LDN:  1.5mg taken each night for 2 weeks, then increasing the dose to 3.0mg taken each night for 2 weeks, then increasing to the terminal dose of 4.5 mg taken each night.  For those interested in making an appointment, please call (713) 522-4037

Appointment Request

You may make an appointment at the Longevity & Stem Cell Centre of Houston in several ways:

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We provide services such as Stem Cell Therapy, Hormone Replacement Therapy (for Menopause and Low Testosterone), Platelet Rich Plasma Therapy, Hyperbaric Oxygen Therapy, and more, we are able to mitigate the debilitating and disabling diseases associated with aging.