The human body prefers physiologic prescriptions and treatments. Testosterone and Estrogen are best delivered as a Subcutaneous Implant. Testosterone pellet implants have many of the ideal features of a long-acting androgen depot [storage], including being safe, highly effective with stable clinical and biochemical effects, economical, providing flexible dosing, and excellent long-acting properties due to a near-zero-order dissolution. A single biodegradable provides stable, effective, and well-tolerated replacement for 4-6 months and pellets can provide excellent androgen replacement in most physiological settings. The only clinically proven way to deliver Growth hormone is as a daily injection.