Stem cells may improve healing of bone fractures in diabetics

People with diabetes are more prone to broken bones and have more trouble recovering from them than the general population. Diabetes has both metabolic and endocrine effects on the quality of a person's bones, weakening them and increasing the risk of fractures. What's more, diabetics' bones often heal less effectively and more slowly than average, turning a single broken bone into a drawn-out ordeal. 

Now, a stem cell treatment has been discovered that may put an end to these problems. Using human bone marrow from non-diabetics, researchers at the National University of Ireland in Galway extracted mesenchymal stem cells and injected them into femur fractures in mice modeled for diabetes. These local injections were repeated daily for 56 days in escalating doses.

The bones that received the stem cells healed more efficiently and ended up much stronger than the fractures that were allowed to heal on their own, suggesting a future for this type of stem cell therapy in diabetic humans. More specifically, the bones treated with the stem cells increased in volume while decreasing in surface area, becoming denser and more resilient.

"This basic science study allows us to better understand the role of stem cells in fracture repair and potential use in treating diabetic patients," said lead author Dr. Cynthia Coleman in a press statement. "Stem cells represent an exciting potential for improving the treatment and lessening the pain and discomfort of diabetic people who break bones."

However, the researchers were quick to add that the mesenchymal stem cells had no effect on the condition of diabetes itself, working only in the bones into which they were injected.

For information about available stem cell therapies in the Houston and Denver areas, contact the Longevity Centres of America today.