New agent, Cacicol®, improves healing time of patients who undergo Keratoconus surgery

Cacicol

If you recently had surgery to treat Keratoconus, a new regenerative medicine called Cacicol® could help you heal faster and with less discomfort. Turkish scientists will be presenting their findings from a new study regarding the medicine at AAO 2015, the 119th annual meeting of the American Academy of Ophthalmology.

Keratoconus is a rare condition in which the cornea—the clear front window of the eye—becomes thin and develops a cone-shaped bulge. In literal terms, Keratoconus means “coned-shaped cornea.” Normally, the cornea has the shape of a dome.

Keratoconus develops because of a decrease in antioxidants in the cornea, causing it to become weak and unable to hold its normal, dome-shaped structure.

To test their findings, researchers used Cacicol® on people who recently had surgery to treat Keratoconus. Their goal was to find whether the agent sped up the process of healing from surgery, thus reducing the possibility patients suffer from complications such as infections and corneal haze.

“Faster healing is clinically important because that helps reduce the risk of complications after surgery,” said the study’s principal author Koray Gumus, M.D.

Researchers treated 30 of 60 patients with drops of Cacicol® and monitored them for three days. In only 24 hours, 83 percent of patients treated with Cacicol® showed tremendous improvement compared to the 13 percent who did not receive the drug. All other aspects of the study remained consistent, such as the type of post-operative topical antibiotics, steroids, artificial tears and bandages.

While researchers have only studied the effects of Cacicol® on Keratoconus, they believe it could work on other eye conditions such as corneal ulcers.